Certified Emergency Nurse (CEN) Test 2025 – 400 Free Practice Questions to Pass the Exam

Osler's nodes are specifically characterized as tender subcutaneous nodules that typically appear on the fingers and toes. These lesions are often associated with infective endocarditis and are indicative of systemic emboli related to the infectious process. The tenderness of these nodes is a key factor that distinguishes them from other types of nodules.

The distinguishing feature of tenderness in Osler's nodes highlights their origin in the context of infectious diseases, particularly how they manifest in response to septicemia or embolic phenomena. Their location on the digits further supports the relationship to infection, as they typically occur in areas where small vessels are prone to embolization.

Other options describe lesions that do not encapsulate the defining characteristics of Osler's nodes. The focus on their painless nature or ulceration, for example, deviates from the specific clinical presentation that defines Osler's nodes.